Some problems and errors in cytogenetic biodosimetry
نویسندگان
چکیده
منابع مشابه
Radiation Dose Estimation by Automated Cytogenetic Biodosimetry.
The dose from ionizing radiation exposure can be interpolated from a calibration curve fit to the frequency of dicentric chromosomes (DCs) at multiple doses. As DC counts are manually determined, there is an acute need for accurate, fully automated biodosimetry calibration curve generation and analysis of exposed samples. Software, the Automated Dicentric Chromosome Identifier (ADCI), is presen...
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Accurate digital image analysis of abnormal microscopic structures relies on high quality images and on minimizing the rates of false positive (FP) and negative objects in images. Cytogenetic biodosimetry detects dicentric chromosomes (DCs) that arise from exposure to ionizing radiation, and determines radiation dose received based on DC frequency. Improvements in automated DC recognition incre...
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Dicentric assay is the international gold standard for cytogenetic biodosimetry after radiation exposure, despite being very labour-intensive, time-consuming, and highly expertise-dependent. It involves the identification of centromeres and structure of solid-stained chromosomes and the enumeration of dicentric chromosomes in a large number of first-division metaphases of cultured T lymphocytes...
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The Fukushima nuclear disaster caused by the earthquake and tsunami on March 11, 2011 is believed to be the worst nuclear accident since the Chernobyl disaster in 1986. The Korean government is providing support to Japan and is also trying to protect the people from the hazards of ionizing radiation. To this end, Korean rescuers have been dispatched to the disaster-struck areas to assist in the...
متن کاملCytogenetic findings in couples with fertility problems
Background: Chromosomal aberrations can be one of the causes of fertility problems, including infertility or frequent abortions. Identification of chromosomal aberrations by clinical diagnostic techniques has been primarily performed through standard karyotyping. In this screening, the prevalence of these disorders were checking in individuals with fertility problems from west population of Ira...
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ژورنال
عنوان ژورنال: Biotechnology & Biotechnological Equipment
سال: 2016
ISSN: 1310-2818,1314-3530
DOI: 10.1080/13102818.2016.1259018